Marvel Studios president and producer Kevin Feige confirmed the news to EW.com.
"He is in the universe now, and the fun of the universe is that characters go back and forth,” Feige said.
It's unknown which Marvel characters will be appearing in the standalone Spider-Man movie, but Joe Russo offered a bit of a tease, with the article noting it's probably a joke.
“Let’s just say … Great Lakes Avengers,” said Joe Russo.
With Marvel characters appearing in the Spider-Man movie, it's probably a good bet that Spider-Man will be appearing in the Avengers: Infinity War movies, which are directed by the Russo Brothers as well.
Tom Holland is playing Spider-Man and debuts in Captain America: Civil War next month followed by the Spider-Man reboot that has a July 7, 2017 release date directed by Jon Watts.